It depends somewhat on your sense of humor, but I'd recommend you check out Things People Said, Adventure Games Live and I Think to start. If you like Things People Said, you might want to check out Computer Stupities next, if you like Adventure Games Live you're going to be busy for awhile but then you might want to hit Murkon's Refuge and maybe Enchanted Forest, and if you like I Think you might want to try the other humor bites that are just Sam and a keyboard like the How To Be series.
Also, if one of your hobbies coincides with part of the site, check that part out. If you're an English major, check out Book a minute, if you love horses check out Equiworks, etc.